V7A (p.Val7Ala) variant of IL10RA (Q13651)
V7A (p.Val7Ala) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
V7A (p.Val7Ala) variant details
- p.Val7Ala
- gnomAD 11-117986487-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.16
- MetaLR 0.23
- MetaSVM -0.96
- CADD 21.00
- PolyPhen-2 0.06
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available