V32A (p.Val32Ala) variant of IL10RA (Q13651)
V32A (p.Val32Ala) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
V32A (p.Val32Ala) variant details
- p.Val32Ala
- gnomAD rs1310932449
- Missense
- Variant Prioritization Score for Impact Estimate 0.45
- REVEL 0.58
- MetaLR 0.55
- MetaSVM -0.03
- CADD 22.10
- PolyPhen-2 0.61
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available