T46I (p.Thr46Ile) variant of IL10RA (Q13651)
T46I (p.Thr46Ile) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
T46I (p.Thr46Ile) variant details
- p.Thr46Ile
- gnomAD 11-117988451-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.129
- REVEL 0.13
- MetaLR 0.22
- MetaSVM -0.96
- CADD 0.03
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available