S31P (p.Ser31Pro) variant of IL10RA (Q13651)
S31P (p.Ser31Pro) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
S31P (p.Ser31Pro) variant details
- p.Ser31Pro
- gnomAD 11-117988405-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.37
- MetaLR 0.39
- MetaSVM -0.72
- CADD 22.50
- PolyPhen-2 0.58
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available