S31C (p.Ser31Cys) variant of IL10RA (Q13651)
S31C (p.Ser31Cys) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S31C (p.Ser31Cys) variant details
- p.Ser31Cys
- 1000Genomes rs201436588
- gnomAD rs201436588
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.25
- MetaLR 0.45
- MetaSVM -0.72
- CADD 22.40
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available