S19L (p.Ser19Leu) variant of IL10RA (Q13651)
S19L (p.Ser19Leu) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
S19L (p.Ser19Leu) variant details
- p.Ser19Leu
- gnomAD 11-117986523-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.12
- MetaLR 0.25
- MetaSVM -0.92
- CADD 12.30
- PolyPhen-2 0.10
- SIFT 0.82
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available