P49L (p.Pro49Leu) variant of IL10RA (Q13651)
P49L (p.Pro49Leu) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
P49L (p.Pro49Leu) variant details
- p.Pro49Leu
- gnomAD 11-117988460-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.10
- MetaLR 0.31
- MetaSVM -0.83
- CADD 9.64
- PolyPhen-2 0.03
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available