P3S (p.Pro3Ser) variant of IL10RA (Q13651)
P3S (p.Pro3Ser) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P3S (p.Pro3Ser) variant details
- p.Pro3Ser
- gnomAD rs1409311372
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.17
- MetaLR 0.10
- MetaSVM -0.95
- CADD 8.35
- PolyPhen-2 0.01
- SIFT 0.51
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available