N50S (p.Asn50Ser) variant of IL10RA (Q13651)
N50S (p.Asn50Ser) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
N50S (p.Asn50Ser) variant details
- p.Asn50Ser
- gnomAD 11-117988463-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.08
- MetaLR 0.28
- MetaSVM -0.94
- CADD 10.60
- PolyPhen-2 0.05
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available