L8M (p.Leu8Met) variant of IL10RA (Q13651)
L8M (p.Leu8Met) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
L8M (p.Leu8Met) variant details
- p.Leu8Met
- gnomAD 11-117986489-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.26
- MetaLR 0.36
- MetaSVM -0.77
- CADD 21.80
- PolyPhen-2 0.60
- SIFT 0.27
- Population evidence available
- Structural context available
- Literature evidence available