L5I (p.Leu5Ile) variant of IL10RA (Q13651)
L5I (p.Leu5Ile) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L5I (p.Leu5Ile) variant details
- p.Leu5Ile
- gnomAD 11-117986480-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.21
- MetaLR 0.35
- MetaSVM -0.69
- CADD 21.70
- PolyPhen-2 0.90
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available