L2Q (p.Leu2Gln) variant of IL10RA (Q13651)
L2Q (p.Leu2Gln) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L2Q (p.Leu2Gln) variant details
- p.Leu2Gln
- gnomAD 11-117986472-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.35
- MetaLR 0.42
- MetaSVM -0.53
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available