L2M (p.Leu2Met) variant of IL10RA (Q13651)
L2M (p.Leu2Met) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L2M (p.Leu2Met) variant details
- p.Leu2Met
- gnomAD 11-117986471-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.21
- MetaLR 0.39
- MetaSVM -0.60
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available