L17F (p.Leu17Phe) variant of IL10RA (Q13651)
L17F (p.Leu17Phe) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L17F (p.Leu17Phe) variant details
- p.Leu17Phe
- Ensembl rs75911988
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.10
- MetaLR 0.17
- MetaSVM -0.91
- CADD 9.31
- PolyPhen-2 0.02
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available