L15I (p.Leu15Ile) variant of IL10RA (Q13651)
L15I (p.Leu15Ile) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L15I (p.Leu15Ile) variant details
- p.Leu15Ile
- gnomAD 11-117986510-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.34
- MetaLR 0.46
- MetaSVM -0.44
- CADD 22.30
- PolyPhen-2 0.69
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available