L15H (p.Leu15His) variant of IL10RA (Q13651)
L15H (p.Leu15His) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
L15H (p.Leu15His) variant details
- p.Leu15His
- gnomAD 11-117986511-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.48
- MetaLR 0.48
- MetaSVM -0.51
- CADD 23.20
- PolyPhen-2 0.88
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available