L13H (p.Leu13His) variant of IL10RA (Q13651)
L13H (p.Leu13His) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L13H (p.Leu13His) variant details
- p.Leu13His
- TOPMed rs2057987204
- gnomAD rs2057987204
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.41
- MetaLR 0.53
- MetaSVM -0.61
- CADD 23.30
- PolyPhen-2 0.97
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available