L12P (p.Leu12Pro) variant of IL10RA (Q13651)
L12P (p.Leu12Pro) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
L12P (p.Leu12Pro) variant details
- p.Leu12Pro
- gnomAD 11-117986502-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.56
- MetaLR 0.50
- MetaSVM -0.41
- CADD 24.70
- PolyPhen-2 0.82
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available