L12I (p.Leu12Ile) variant of IL10RA (Q13651)
L12I (p.Leu12Ile) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L12I (p.Leu12Ile) variant details
- p.Leu12Ile
- gnomAD 11-117986501-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.14
- MetaLR 0.20
- MetaSVM -0.94
- CADD 9.31
- PolyPhen-2 0.03
- SIFT 0.47
- Population evidence available
- Structural context available
- Literature evidence available