L12F (p.Leu12Phe) variant of IL10RA (Q13651)
L12F (p.Leu12Phe) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
L12F (p.Leu12Phe) variant details
- p.Leu12Phe
- gnomAD 11-117986501-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.13
- MetaLR 0.25
- MetaSVM -0.96
- CADD 11.30
- PolyPhen-2 0.03
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available