I42V (p.Ile42Val) variant of IL10RA (Q13651)
I42V (p.Ile42Val) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
I42V (p.Ile42Val) variant details
- p.Ile42Val
- ExAC rs761039534
- gnomAD rs761039534
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.21
- MetaLR 0.25
- MetaSVM -0.99
- CADD 6.84
- PolyPhen-2 0.02
- SIFT 0.75
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available