I42F (p.Ile42Phe) variant of IL10RA (Q13651)
I42F (p.Ile42Phe) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
I42F (p.Ile42Phe) variant details
- p.Ile42Phe
- gnomAD 11-117988438-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.46
- MetaLR 0.46
- MetaSVM -0.14
- CADD 21.60
- PolyPhen-2 0.57
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available