H44Y (p.His44Tyr) variant of IL10RA (Q13651)
H44Y (p.His44Tyr) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
H44Y (p.His44Tyr) variant details
- p.His44Tyr
- gnomAD 11-117988444-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.12
- MetaLR 0.25
- MetaSVM -0.89
- CADD 9.49
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available