H41R (p.His41Arg) variant of IL10RA (Q13651)
H41R (p.His41Arg) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
H41R (p.His41Arg) variant details
- p.His41Arg
- gnomAD rs1265212565
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- REVEL 0.72
- MetaLR 0.55
- MetaSVM 0.08
- CADD 24.70
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available