H22Y (p.His22Tyr) variant of IL10RA (Q13651)
H22Y (p.His22Tyr) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
H22Y (p.His22Tyr) variant details
- p.His22Tyr
- gnomAD rs1203522961
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.19
- MetaLR 0.20
- MetaSVM -0.84
- CADD 13.30
- PolyPhen-2 0.01
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available