H22Q (p.His22Gln) variant of IL10RA (Q13651)
H22Q (p.His22Gln) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
H22Q (p.His22Gln) variant details
- p.His22Gln
- TOPMed rs1483805691
- gnomAD rs1483805691
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.13
- MetaLR 0.25
- MetaSVM -0.92
- CADD 3.59
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available