H22N (p.His22Asn) variant of IL10RA (Q13651)
H22N (p.His22Asn) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
H22N (p.His22Asn) variant details
- p.His22Asn
- gnomAD rs1203522961
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.18
- MetaLR 0.25
- MetaSVM -0.84
- CADD 13.90
- PolyPhen-2 0.24
- SIFT 0.28
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available