H22D (p.His22Asp) variant of IL10RA (Q13651)
H22D (p.His22Asp) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
H22D (p.His22Asp) variant details
- p.His22Asp
- gnomAD 11-117986531-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.19
- MetaLR 0.25
- MetaSVM -0.84
- CADD 18.30
- PolyPhen-2 0.24
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available