E37Q (p.Glu37Gln) variant of IL10RA (Q13651)
E37Q (p.Glu37Gln) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
E37Q (p.Glu37Gln) variant details
- p.Glu37Gln
- gnomAD 11-117988423-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.09
- MetaLR 0.17
- MetaSVM -0.99
- CADD 21.30
- PolyPhen-2 0.04
- SIFT 0.17
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available