E35V (p.Glu35Val) variant of IL10RA (Q13651)
E35V (p.Glu35Val) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
E35V (p.Glu35Val) variant details
- p.Glu35Val
- gnomAD rs1203213796
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.38
- MetaLR 0.27
- MetaSVM -0.85
- CADD 22.30
- PolyPhen-2 0.16
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available