E35K (p.Glu35Lys) variant of IL10RA (Q13651)
E35K (p.Glu35Lys) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
E35K (p.Glu35Lys) variant details
- p.Glu35Lys
- gnomAD 11-117988417-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.13
- MetaLR 0.22
- MetaSVM -0.92
- CADD 19.90
- PolyPhen-2 0.10
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available