C4R (p.Cys4Arg) variant of IL10RA (Q13651)
C4R (p.Cys4Arg) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
C4R (p.Cys4Arg) variant details
- p.Cys4Arg
- Ensembl rs2057986596
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.12
- MetaLR 0.05
- MetaSVM -0.92
- CADD 6.04
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available