A36T (p.Ala36Thr) variant of IL10RA (Q13651)
A36T (p.Ala36Thr) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
A36T (p.Ala36Thr) variant details
- p.Ala36Thr
- TOPMed rs1475635471
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.61
- MetaLR 0.50
- MetaSVM 0.02
- CADD 28.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available