A21V (p.Ala21Val) variant of IL10RA (Q13651)
A21V (p.Ala21Val) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- TOPMed rs1288585880
- gnomAD rs1288585880
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.38
- MetaLR 0.35
- MetaSVM -0.62
- CADD 22.50
- PolyPhen-2 0.39
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available