A21T (p.Ala21Thr) variant of IL10RA (Q13651)
A21T (p.Ala21Thr) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- gnomAD rs1442855942
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.29
- MetaLR 0.26
- MetaSVM -0.79
- CADD 18.00
- PolyPhen-2 0.08
- SIFT 0.20
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available