A21S (p.Ala21Ser) variant of IL10RA (Q13651)
A21S (p.Ala21Ser) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 11-117986528-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.24
- MetaLR 0.29
- MetaSVM -0.77
- CADD 18.10
- PolyPhen-2 0.32
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available