A21P (p.Ala21Pro) variant of IL10RA (Q13651)
A21P (p.Ala21Pro) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
A21P (p.Ala21Pro) variant details
- p.Ala21Pro
- gnomAD 11-117986528-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.51
- MetaLR 0.43
- MetaSVM -0.53
- CADD 22.70
- PolyPhen-2 0.92
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available