A21D (p.Ala21Asp) variant of IL10RA (Q13651)
A21D (p.Ala21Asp) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
A21D (p.Ala21Asp) variant details
- p.Ala21Asp
- gnomAD 11-117986529-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.462
- REVEL 0.51
- MetaLR 0.45
- MetaSVM -0.47
- CADD 23.70
- PolyPhen-2 0.81
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available