T31N (p.Thr31Asn) variant of IL10 (Interleukin-10)
T31N (p.Thr31Asn) in IL10 (Interleukin-10) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T31N (p.Thr31Asn) variant details
- p.Thr31Asn
- ExAC rs752491913
- TOPMed rs752491913
- gnomAD rs752491913
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.0765
- REVEL 0.04
- CADD 7.96
- SIFT 0.49
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available