S19T (p.Ser19Thr) variant of IL10 (Interleukin-10)
S19T (p.Ser19Thr) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S19T (p.Ser19Thr) variant details
- p.Ser19Thr
- gnomAD 1-206772380-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.23
- CADD 14.20
- PolyPhen-2 0.33
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available