S19R (p.Ser19Arg) variant of IL10 (Interleukin-10)
S19R (p.Ser19Arg) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
S19R (p.Ser19Arg) variant details
- p.Ser19Arg
- gnomAD 1-206772379-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.34
- AlphaMissense 0.26
- MetaLR 0.38
- MetaSVM -0.25
- CADD 19.40
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available