R45P (p.Arg45Pro) variant of IL10 (Interleukin-10)
R45P (p.Arg45Pro) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
R45P (p.Arg45Pro) variant details
- p.Arg45Pro
- gnomAD 1-206772302-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.654
- REVEL 0.72
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available