R45* (p.Arg45Ter) variant of IL10 (Interleukin-10)
R45* (p.Arg45Ter) in IL10 (Interleukin-10) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
R45* (p.Arg45Ter) variant details
- p.Arg45Ter
- 1000Genomes rs570050304
- ExAC rs570050304
- gnomAD rs570050304
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.667
- CADD 35.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available