N100K (p.Asn100Lys) variant of IL10 (Interleukin-10)
N100K (p.Asn100Lys) in IL10 (Interleukin-10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
N100K (p.Asn100Lys) variant details
- p.Asn100Lys
- NCI-TCGA TCGA novel
- Ensembl rs2102439232
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.08
- CADD 15.10
- PolyPhen-2 0.20
- SIFT 0.93
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available