M57V (p.Met57Val) variant of IL10 (Interleukin-10)
M57V (p.Met57Val) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
M57V (p.Met57Val) variant details
- p.Met57Val
- gnomAD 1-206771412-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.15
- CADD 18.10
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available