L91V (p.Leu91Val) variant of IL10 (Interleukin-10)
L91V (p.Leu91Val) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
L91V (p.Leu91Val) variant details
- p.Leu91Val
- ExAC rs745801059
- gnomAD rs745801059
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- REVEL 0.76
- CADD 24.20
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available