L7V (p.Leu7Val) variant of IL10 (Interleukin-10)
L7V (p.Leu7Val) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
L7V (p.Leu7Val) variant details
- p.Leu7Val
- ExAC rs772299982
- TOPMed rs772299982
- gnomAD rs772299982
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.46
- CADD 21.10
- PolyPhen-2 0.68
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available