L7F (p.Leu7Phe) variant of IL10 (Interleukin-10)
L7F (p.Leu7Phe) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- ExAC rs772299982
- TOPMed rs772299982
- gnomAD rs772299982
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.36
- CADD 17.90
- PolyPhen-2 0.21
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available