L64S (p.Leu64Ser) variant of IL10 (Interleukin-10)
L64S (p.Leu64Ser) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L64S (p.Leu64Ser) variant details
- p.Leu64Ser
- Ensembl rs756548976
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.06
- CADD 8.88
- PolyPhen-2 0.27
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available