L37P (p.Leu37Pro) variant of IL10 (Interleukin-10)
L37P (p.Leu37Pro) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
L37P (p.Leu37Pro) variant details
- p.Leu37Pro
- gnomAD 1-206772326-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.692
- REVEL 0.81
- CADD 24.60
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available